"I don't think it was taken serious enough," she said.

German authorities suspect Brückner of murder and fear that if he is not charged with anything new he will disappear following his release. British police continue to treat the case as a missing persons investigation.Brückner has repeatedly denied any involvement.

German police have a European warrant, which has been approved by Portuguese prosecutors, will allow them to conduct searches on private land. This week's search is expected to span across 21 different plots of land.Officials have not disclosed if they are conducting this latest search in Portugal based on any new information, making it appear as if they are taking one last look in places where evidence or a body could have been hiddenPortuguese authorities have also named Brückner as a formal suspect, or "arguido". They said they will hand over any evidence seized in the latest search to German authorities.

The Met Police, which said this week that it was aware of the searches being carried out by German police in Portugal, continues its investigation into Madeleine's disappearance.The case, known as Operation Grange, has been ongoing since 2011 and has cost around £13.3m to date.

On the night Madeleine disappeared, her parents had been at dinner with friends at a restaurant a short distance away from the ground-floor apartment she and her younger twin siblings were asleep in.

Her mother, Kate, discovered she was missing at around 22:00.Another Isro experiment involves growing three strains of microalgae which could be used as food, fuel or even in life support systems and this will help identify the most suitable ones for growing in microgravity, she says.

The Isro projects would also investigate how tardigrades - micro-animals on Earth that can survive extreme environments - would fare in space."The project will examine the revival of dormant tardigrades, count the number of eggs laid and hatched during a mission, and compare space-flown versus ground control populations," Ms Mitra says.

The other experiments aim to identify how muscle loss occurs in space and how it can be treated; and the physical and cognitive impact of using computer screens in microgravity."The research will study how gaze fixation and rapid eye movements are affected by being in space, and how this may affect an astronaut's stress and wellbeing. The results could influence future spacecraft computer design and interaction," she says.