内容摘要：That is why experts recommend that patients improve their diet and increase the amount of exercise they take while on the treatment.

That is why experts recommend that patients improve their diet and increase the amount of exercise they take while on the treatment.

Both drugs led to substantial weight loss, but Mounjaro's 20% weight reduction, after 72 weeks of treatment, exceeded the 14% from Wegovy.The trial, which was paid for by Eli Lilly, the manufacturer of Mounjaro, involved 750 obese people, with an average weight of 113kg (nearly 18 stone).

Previous clinical studies suggested that - when combined with changes to their diet, exercise and behavioural support - Wegovy users could lose more than 10% of their body weight after a year on the treatment. Other trials also suggested Mounjaro users might lose up to a fifth of their weight.Crucially, users of either drug can put weight back on once they stop treatment.Wegovy is available on the NHS in England, Wales and Scotland.

It must be prescribed by a weight management specialist, and access to these is restricted.To qualify, adults must be obese (with a BMI of at least 35) and have at least one pre-existing weight-related health condition such as high blood pressure.

People with cardiovascular disease who are classed as overweight, but not quite obese, can also be given the drug.

Patients should follow a diet and physical activity programme, and the drug should be only prescribed for a maximum of two years, according to NHS guidelines.Although we now know that DragonForce is behind both, it is still not clear who the actual hackers are.

DragonForce offers cyber criminal affiliates various services on their darknet site in exchange for a 20% cut of any ransoms collected.Anyone can sign up and use their malicious software to scramble a victim's data or use their darknet website for their public extortion.

Nothing has appeared on the criminal's darknet leak site about either Co-op or M&S but the hackers told the BBC last week that they were having IT issued of their own and would be posting information "very soon."Some researchers say DragonForce are based in Malaysia, while others say Russia. Their email to M&S implies that they are from China.