内容摘要：The Associated Press’ climate and environmental coverage receives financial support from multiple private foundations. AP is solely responsible for all content. Find AP’s

The Associated Press’ climate and environmental coverage receives financial support from multiple private foundations. AP is solely responsible for all content. Find AP’s

, most of them caused by a misstep hidden within their genes. Some conditions can be caught early and treated—but in parts of Africa where population data and resources are scarce, many people go undiagnosed. Rodriguez is trying to change that by connecting patients with genetic testing and medical support, while gathering key data from those patients and their families.“Most rare disease data has been collected from people of European ancestry, so we have very little knowledge about what’s happening in other parts of the world, mainly in Africa,” Rodriguez said.

Ndeye Lam looks at photos of her deceased daughter Mariama who died at age 13 of a rare genetic disease, in Dakar, Senegal, Saturday, Jan. 11, 2025. (AP Photo/Annika Hammerschlag)Ndeye Lam looks at photos of her deceased daughter Mariama who died at age 13 of a rare genetic disease, in Dakar, Senegal, Saturday, Jan. 11, 2025. (AP Photo/Annika Hammerschlag)His research is funded by organizations including the La Caixa Foundation in Spain and the National Ataxia Foundation in the United States. And he has consulted with scientists in China, France, Boston, and elsewhere around the world, documenting rare diseases and novel disease-causing gene variants.

That research is creating a library of genetic data for scientists and clinicians. Patients in Senegal are benefiting, too, with a path to diagnosis.Fatoumata Sané holds her daughter Aissata, 8, who suffers from a rare genetic disease, at their home in Dakar, Senegal, Saturday, Jan. 11, 2025. (AP Photo/Annika Hammerschlag)

Fatoumata Sané holds her daughter Aissata, 8, who suffers from a rare genetic disease, at their home in Dakar, Senegal, Saturday, Jan. 11, 2025. (AP Photo/Annika Hammerschlag)

In Guediawaye, Fatoumata Binta Sané’s daughter Aissata has glutaric acidemia type I, an inherited disorder in which the body can’t process certain proteins properly. Her arms and legs are tightly drawn up toward her chest. She can’t walk or reach for things, speak, sit on her own or hold her head up. Sané cradles Aissata in her arms constantly, and the 8-year-old smiles at the sound of her mother’s voice.Piotr Buras, head of the European Council on Foreign Relations’ Warsaw office, says Poland is part of a larger pattern in which voters turn to populist forces amid rapid social change. But he also cites local factors, such as disillusionment with Tusk’s coalition.

That coalition, which spans the ideological spectrum, has struggled to agree on key issues, including liberalizing the abortion law — a campaign promise. Meanwhile, outgoing conservative President Andrzej Duda has blocked parts of Tusk’s agenda. Observers say the coalition’s voters must be highly mobilized on Sunday to defeat Nawrocki.The liberal presidential candidate Rafal Trzaskowski, front left, waves as he and Polish prime minister Donald Tusk, front right, take part in a march one week ahead of a decisive presidential election in Warsaw, Poland on Sunday, May 25, 2025. (AP Photo/Czarek Sokolowski)

The liberal presidential candidate Rafal Trzaskowski, front left, waves as he and Polish prime minister Donald Tusk, front right, take part in a march one week ahead of a decisive presidential election in Warsaw, Poland on Sunday, May 25, 2025. (AP Photo/Czarek Sokolowski)Many votes in the first round went to protest candidates. Among voters aged 18–29, over 35% backed Mentzen, and nearly 20% supported a left-wing candidate, Adrian Zandberg, according to exit polls.