内容摘要：The charity's spokesperson, Deborah Hyde, says: "By registering as a donor, you could give hope not just to Mason, but countless others from all backgrounds, who are relying on the stem cell register for a second chance at life.

The charity's spokesperson, Deborah Hyde, says: "By registering as a donor, you could give hope not just to Mason, but countless others from all backgrounds, who are relying on the stem cell register for a second chance at life.

In theory, that means a transgender man or woman should use facilities that correspond to their biological sex.However, this is likely to present other difficulties as the person will be presenting as their gender identity to the outside world.

Baroness Falkner argues that transgender people should use "their power of advocacy" to persuade organisations to provide third spaces such as unisex toilets.Cases such as that ofafter refusing to share a changing room with a transgender doctor, are likely to be reviewed.

NHS Fife, the health board involved in the case, told the BBC that it noted the clarity provided by the ruling and would "carefully consider the judgment".Following the ruling, trans women cannot compete in women's sport, the EHRC says.

Sport has been one of the most hotly contested areas in the debate about gender. In recent years, many sports have tightened rules around transgender athletics at elite levels.

Athletics, cycling and aquatics, for example, have banned transgender women from taking part in women's events."This leadership upset comes amid weaker consumer sentiment which has meant footfall at its stores has fallen - and the chain has been losing market share in the UK."

She said that internationally the company has performed well, but added: "There could be uncertainty ahead about the speed of expansion given the change of boss."Following Mr Marchant's "immediate" departure, ABF's finance director Eoin Tonge will become Primark's interim chief executive.

The firm's financial controller, Joana Edwards, will step into Mr Tonge's role. The company said: "Both executives have the experience to perform these roles well."ABF is majority-owned by the billionaire Weston family who, until 2021, owned the department store Selfridges.