Black women are more than three times as likely to
“We designed this facility to protect the pigs against contamination from the environment and from people,” said Matthew VonEsch of United Therapeutics, Revivicor’s parent company. “Every person that enters this building is a possible pathogen risk.”The Associated Press got a peek at what it takes to clone and raise designer pigs for their organs – including a $75 million “designated pathogen-free facility” built to meet Food and Drug Administration safety standards for xenotransplantation.
Thousands of Americans each yearfor a transplant, and many experts acknowledge there never will be enough human donors to meet the need.Animals offer the tantalizing promise of a ready-made supply. After decades of failed attempts, companies including Revivicor,
and Makana Therapeutics are engineering pigs to be more humanlike.So far in the U.S. there have been four “compassionate use” transplants, last-ditch experiments into dying patients — two hearts and two kidneys. Revivicor provided both hearts and one of the kidneys. While the four patients died within a few months, they offered valuable lessons for researchers ready to try again in people who aren’t quite as sick.
Now the FDA is evaluating promising results from experiments in donated human bodies and awaiting results of additional studies of pig organs in baboons before deciding next steps.
They’re semi-custom organs — “we’re growing these pigs to the size of the recipient,” Ayares noted — that won’t show the wear-and-tear of aging or chronic disease like most organs donated by people.The nutrition standards are required to meet the federal Dietary Guidelines for Americans, which are reviewed and revised every five years. Since 1985, those guidelines have recommended that Americans older than age 2 consume low-fat or fat-free dairy.
The 2025-2030 dietary guidelines are set for revision this year under a joint effort by USDA and the Department of Health and Human Services. A panel of scientific experts who reviewed evidence regarding milk fat content recommended that the U.S. policy remain the same.changes in the federal nutrition program after the 2010 law have slowed the rise in obesity among U.S. kids — even teenagers, said Deanna Hoelscher, a nutrition expert and researcher at the University of Texas Health Science Center who served on the dietary guidelines committee.
“We didn’t find enough definitive evidence to change a policy that’s been in place that has shown good outcomes to date,” Hoelscher said.Although there was limited evidence that consuming higher-fat dairy rather than lower-fat dairy could benefit very young children, there wasn’t enough evidence to make a conclusion for older kids and teens, she said. There were “substantial concerns” with the consistency, quantity and risk of bias in the existing research, the report concluded.