内容摘要：. When one commenter asked if these bites might be good frozen, people replied that they are "definitely putting them in the freezer."

. When one commenter asked if these bites might be good frozen, people replied that they are "definitely putting them in the freezer."

One reason this discovery is so important is because it could help drug developers design more precise treatments. By focusing only on the nerve cells that reduce appetite and, future medications could provide weight loss benefits without the drawbacks of nausea or muscle loss.

That’s especially relevant for people who already have lower muscle mass, such as older adults. Losing more lean tissue can lead to problems like frailty or even sarcopenia, a condition marked by extreme muscle wasting.The new study also offers insight into the wider role of the dorsal vagal complex in controlling energy balance. Even though semaglutide can’t move freely through the brain, it seems to use these “entry points” like the DVC to activate deeper networks that affect hunger and metabolism.Other brain areas connected to this region are also involved in feelings of fullness and hormone control. The researchers found that when the

were removed, these downstream targets were much less active—even when semaglutide was still in the system.Yet, structures linked to nausea were still triggered, showing that the positive and negative effects of semaglutide follow different brain circuits. That opens the door to developing new drugs that could mimic semaglutide's benefits while bypassing the pathways that cause people to feel sick.

The team’s findings were published in the journal

. It’s one of the first studies to clearly map the brain activity behind semaglutide’s effects and separate the benefits from the side effects at the neuron level.The Caribbean is full of gorgeous resorts, but one of the biggest mistakes I see first-time visitors make is never leaving the property. Every time I travel to an island, I make a point to leave the resort and check out nearby attractions.

One of my favorite recent travel experiences was a day trip in Jamaica, where I was able to float down the Martha Brae River and climb Dunn's River Falls.If you're unsure of what activities are available, check out some reputable tours online or ask your hotel's concierge for recommendations. If you do plan to leave the resort, be sure to do your research and take standard safety precautions.

The Caribbean is known for its, which are convenient for families with small children or large groups of friends.