内容摘要：, one travel company is offering its first-ever activist-led trips designed to help travelers engage in protecting America's parks.

, one travel company is offering its first-ever activist-led trips designed to help travelers engage in protecting America's parks.

. A small study of 26 people found that a single low dose of the chemicaland increased brain activity during thinking tasks. Another study by the same researchers found that methylene blue changed how different parts of the brain connected, though it

Although some studies in people have shown hints that methylene blue may be beneficial for some brain-related issues, such as, such studies to date have been small. This suggests that while there may be patient circumstances where methylene blue is beneficial, researchers have not yet pinned down what those are.Methylene blue is generally safe when used under medical supervision. However, the chemical has some serious risks.

For one thing, it can interact with widely used medications. Methylene blue, whose job is to break down an important brain chemical, serotonin. Many commonly used

along with these medicines

, which can lead to agitation, confusion, high fever, rapid heart rate, muscle stiffness and, in severe cases, seizures or even death.. (I’m leaving aside Glera, the grape of

; that’s a different story.)But for me, the true joy lies in Italy’s less well-known, native varieties. Coastal Vermentinos from Liguria and Sardinia with their citrus-zest snap; Etna whites, which suggest their volcanic origins in a kind of stony intensity; bright, faintly almondy Verdicchios from Marche — all of these wake you up with zippy acidity and little to no oak influence, and they tend to be appealingly affordable as well.

Fill a cooler with ice and bottles, invite over some friends, and save those brooding Amarones until December, when the wintry winds start whipping by once again. Here are 21 refreshing Italian white wines to seek out right now.The Tasca d’Almerita family’s Regaleali estate in the center of Sicily is a do-not-miss visit, and this tingly, grapefruity white made from Cataratto comes from the vineyards surrounding the beautiful manor house there.